Capabilities

VectorBuilder Inc. is the world’s largest provider of custom vectors for viral and non-viral gene delivery. Our CRO services include library construction and screening, stable cell line generation, BAC recombineering, mRNA synthesis, and preclinical testing of vector efficacy and safety profiles. CDMO services include GMP manufacturing (plasmid DNA, viral vectors, mRNA, etc.), process development, analytical development, cell banking, fill/finish, and regulatory support.

Core Competencies

  • VECTOR CLONING
  • VIRUS PACKAGING
  • LIBRARY CONSTRUCTION
  • AAV CAPSID EVOLUTION
  • mRNA GENE DELIVERY SOLUTIONS
  • CRISPR AND shRNA SOLUTIONS
  • STABLE CELL LINE GENERATION
  • PLASMID DNA PREPARATION

Differentiators

VectorBuilder Inc has developed proprietary technologies and reagents that significantly improve virus packaging in terms of titer, purity, viability, and consistency. Our packaging protocols are also optimized for the viral vector systems used in cloning services. We have about 100,000 sq ft of modern GMP facilities with state-of-the-art equipment. Our facilities meet GMP regulations of the US, EU, Japan, China, and PIC/S. They are suitable for clinical trial Phase I/II/III manufacturing.

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